Rejuran

Rejuran injections are used in skin rejuvenation procedures for collagen stimulation in the upper layers of the skin.

Rejuran is a gel formation of Polynucleotides (PN) made from wild salmon DNA fragments, and has been used in Korea since 2014.

These Polynucleotides promote skin regeneration, hydration, improve elasticity, and reduce the appearance of fine lines and wrinkles when injected into the skin.

FAQS

+ How does Rejuran work?

Rejuran works by stimulating fibroblast within the skin, resulting in increased collagen production, thereby increasing skin thickness and improving skin tightness. Rejuran is also advantageous for the skin by activating anti-inflammatory responses and promoting wound healing.

+ Who is suitable for Rejuran treatment?

A consultation is required to determine individual suitability for Rejuran. Rejuran may assist in the following:

  • Fine lines and wrinkles
  • Uneven skin tone and texture
  • Loss of elasticity: individuals experiencing lost of skin elasticity, which can contribute to sagging of the skin, may find the collagen stimulation from Rejuran beneficial.
  • Overall skin rejuvenation
  • Dark eye circles and dull skin
  • Acne and other scarring

+ Who is not suitable for Rejuran?

  • Active skin conditions or infection
  • Recent cosmetic procedures: it is advisable to wait a certain period of time after undergoing other cosmetic procedures such as chemical peel, or laser treatments, before considering Rejuran.
  • Autoimmune disorders
  • Pregnancy and breast feeding
  • Unrealistic Expectations: Rejuran provide gradual improvement to the skin over time. Individuals with unrealistic expectations or those seeking immediate dramatic results may not be a suitable candidate for this treatment.

+ What happens during Rejuran treatment?

Patients are requested to arrive 30 minutes prior to their injection appointment time for application of topical anaesthetic. It may be useful to take two paracetamol prior to the procedure. Rejuran is administered by the doctor to the treatment area. Follow up appointment will be arranged in 2 to 4 weeks for review.

+ What are the risks and side-effects?

Risks and side effects associated with Rejuran treatment include:

  • Lumps and bumps, which may look similar to mosquito bites. These usually subside within 24 to 48 hours.
  • Bruising and swelling may occur, typically resolving within a few days.
  • Infection is rare
  • Allergy reaction is rare

+ What to avoid after Rejuran

  • Excessive sun exposure, apply sunscreen with high SPF to shield the skin from sun and prevent pigmentation.
  • Avoid hot environments like saunas immediately after treatment
  • Intense physical activity
  • Harsh skincare products
  • Refrain from excessive massage or rubbing of the treated area.

+ How frequently is treatment required?

The number of Rejuran treatments needed can vary between individuals depending on specific concerns being addressed and the health condition of the skin. Generally, treatments are performed as a series of three sessions, space 2 to 4 weeks apart. Maintenance treatment is recommended 6 to 12 monthly.

+ Are Rejuran injections painful?

Topical numbing cream is applied before treatment to numb the area to be treated. Paracetamol two tablets may be taken prior to the procedure. Following treatment, temporary discomfort around the injection site may occur as the anaesthetic cream wears off.

+ How long do the results last?

Due to the natural biological ageing process, Rejuran results are not permanent. Individual results vary, and factors such as individual skin characteristics, lifestyle, choices, and specific concerns being addressed can influence the longevity of the results. Collagen stimulation initiated by Rejuran tends to have a gradual and cumulative effect, with results becoming noticeable after a series of sessions. Depending on the patient’s age, skin quality, and general health, a course of three treatment sessions 2 to 3 weeks apart may be recommended. Maintenance treatment every 6 to 12 months is recommended.

+ What is the difference between Rejuran, Bio-remodelling and Bio-stimulators?

Rejuran

  • Composition: Rejuran is composed of Polynucleotides, which are DNA fragment sourced from salmon DNA. These Polynucleotides stimulate collagen production and promote skin rejuvenation in the upper layers of the skin.
  • Mechanism of action: Rejuran works by activating the natural regenerative processes within the upper layers of the skin, leading to increase collagen and elastin production.
  • Intended outcome: Rejuran is primarily used for skin rejuvenation, addressing fine lines, wrinkles and skin texture.

Bio-remodeling

  • Composition: Profhilo is composed of both high and low molecular weight of their active hydrating ingredients.
  • Mechanism of action: remodelling diffuses within the skin, hydrating and stimulating the production of collagen and elastin, aiming to provide overall skin hydration.
  • Intended outcome: Bio-remodeling It often used for skin laxity where hydration is required.

Bio-stimulators

  • Composition: Bio-stimulator Radiesse it’s made from biodegradable biocompatible polymer.
  • Mechanism of action: Bio-stimulators work by stimulating the growth of collagen in the deep layers of the skin, providing a gradual increase in volume and skin firmness.
  • Intended outcome: Bio-stimulators typically used when, in addition to collagen production, it is recommended to restore some volume in areas that have experienced age related volume loss as well.